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SATB2 抗体 (N-Term)

SATB2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500674
发货至: 中国
  • 抗原 See all SATB2 抗体
    SATB2 (SATB Homeobox 2 (SATB2))
    抗原表位
    • 16
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 68
    • 34
    • 28
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 59
    • 9
    克隆类型
    • 45
    • 23
    多克隆
    标记
    • 33
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SATB2 antibody is un-conjugated
    应用范围
    • 50
    • 23
    • 16
    • 14
    • 14
    • 10
    • 9
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects SATB2 at N-term. It will not cross-react with SATB1.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    SATB2 antibody was raised against a 16 amino acid peptide near the amino terminus of the human SATB2.
    亚型
    IgG
    Top Product
    Discover our top product SATB2 Primary Antibody
  • 应用备注
    ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SATB2 (SATB Homeobox 2 (SATB2))
    别名
    SATB2 (SATB2 产品)
    别名
    RGD1562369 antibody, mKIAA1034 antibody, SATB homeobox 2 antibody, special AT-rich sequence binding protein 2 antibody, SATB2 antibody, satb2 antibody, Satb2 antibody
    背景
    Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. Recent experiments have shown that SATB2 interacts with histone deacetylase 1 and metastasis-associated protein 2, two proteins that are involved in chromatin remodeling, suggesting that SATB2 may also be involved in mediating epigenetic influences during cortical development. At least two isoforms of SATB2 are known to exist.Synonyms: DNA-binding protein SATB2, KIAA1034, Special AT-rich sequence-binding protein 2
    基因ID
    23314
    UniProt
    Q9UPW6
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