RUSC1 抗体 (C-Term)
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- 抗原 See all RUSC1 抗体
- RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RUSC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects NESCA.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- RUSC1 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human RUSC1.
- 亚型
- IgG
- Top Product
- Discover our top product RUSC1 Primary Antibody
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anti-RUN and SH3 Domain Containing 1 (RUSC1) (AA 231-433) antibody
RUSC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RUN and SH3 Domain Containing 1 (RUSC1) (AA 1-433) antibodyRUSC1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RUN and SH3 Domain Containing 1 (RUSC1) (AA 1-320) antibodyRUSC1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RUN and SH3 Domain Containing 1 (RUSC1) antibodyRUSC1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
- 别名
- NESCA (RUSC1 产品)
- 别名
- NESCA antibody, 2210403N08Rik antibody, AA408288 antibody, RUN and SH3 domain containing 1 antibody, RUSC1 antibody, Rusc1 antibody
- 背景
- RUSC1, also known as NESCA, shares with the related protein RUSC2 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC1 is an adapter protein that can bind to the TrkA receptor and is necessary in the NGF-induced neurite growth of PC12 cells. RUSC1 has also been shown to interact with IkappaB kinase- (IKK-) gamma, the regulatory subunit of the IKK complex that is required for NF-kappaB activation in many signaling pathways such as TNF-R or the TLR pathways. RUSC1 can also bind to the E3 ubiquitin ligase TRAF6, which then catalyzes RUSC1 polyubiquitination. Since overexpression of RUSC1 strongly inhibits TRAF6-mediated polyubiquitination of IKK-gamma, RUSC1 may be a link in the IKK-gamma-mediated NF-kappaB activation pathway.Synonyms: RUN and SH3 domain-containing protein 1, RUSC1
- 基因ID
- 23623
- NCBI登录号
- NP_001098673
- UniProt
- Q9BVN2
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