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PDCD5 抗体 (N-Term)

PDCD5 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500465
发货至: 中国
  • 抗原 See all PDCD5 抗体
    PDCD5 (Programmed Cell Death 5 (PDCD5))
    抗原表位
    • 15
    • 9
    • 9
    • 7
    • 7
    • 5
    • 4
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 54
    • 2
    克隆类型
    • 54
    • 1
    多克隆
    标记
    • 20
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDCD5 antibody is un-conjugated
    应用范围
    • 39
    • 22
    • 13
    • 13
    • 9
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects PDCD5 at N-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    PDCD5 antibody was raised against a 13 amino acid peptide from near the amino terminus of human PDCD5.
    亚型
    IgG
    Top Product
    Discover our top product PDCD5 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PDCD5 (Programmed Cell Death 5 (PDCD5))
    别名
    PDCD5 (PDCD5 产品)
    别名
    zgc:56315 antibody, tfar19 antibody, DKFZp468P187 antibody, TFAR19 antibody, 2200003D22Rik antibody, AA408513 antibody, Tfar19 antibody, programmed cell death 5 antibody, programmed cell death 5 S homeolog antibody, DNA-binding protein antibody, pdcd5 antibody, PDCD5 antibody, pdcd5.S antibody, SSO_RS01750 antibody, Pdcd5 antibody
    背景
    Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis (5). The nucleotide polymorphisms in the 5?-upstream region of PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer.Synonyms: Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TFAR19
    基因ID
    9141
    NCBI登录号
    NP_004699
    UniProt
    O14737
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