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FAM120A 抗体 (Center)

FAM120A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499822
发货至: 中国
  • 抗原 See all FAM120A 抗体
    FAM120A (Family with Sequence Similarity 120A (FAM120A))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 9
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 8
    • 1
    克隆类型
    • 8
    • 1
    多克隆
    标记
    • 9
    This FAM120A antibody is un-conjugated
    应用范围
    • 9
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to FAM120A.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    FAM120A antibody was raised against an 18 amino acid peptide from near the center of human FAM120A.
    亚型
    IgG
    Top Product
    Discover our top product FAM120A Primary Antibody
  • 应用备注
    ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    FAM120A (Family with Sequence Similarity 120A (FAM120A))
    别名
    FAM120A (FAM120A 产品)
    别名
    MGC89333 antibody, fam120a antibody, C9orf10 antibody, Ossa antibody, DNAPTP1 antibody, DNAPTP5 antibody, OSSA antibody, RGD1306643 antibody, family with sequence similarity 120A antibody, family with sequence similarity 120, member A antibody, fam120a antibody, Fam120a antibody, FAM120A antibody
    背景
    FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31. FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain. As a novel RNA-binding protein, FAM120A is a critical component of the oxidative stress-induced survival signaling. It may participate in mRNA transport in the cytoplasm. FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress. Blocking of the survival signaling mediated by FAM120A, which sensitizes the cancer cells to stress-induced apoptosis, may be a novel therapeutic approach for gastric scirrhous carcinoma cells.Synonyms: C9orf10, Constitutive coactivator of PPAR-gamma-like protein 1, KIAA0183, OSSA, Oxidative stress-associated Src activator, Protein FAM120A
    基因ID
    23196
    NCBI登录号
    NP_055427
    UniProt
    Q9NZB2
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