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ATP11A 抗体 (N-Term)

ATP11A 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783659
发货至: 中国
  • 抗原 See all ATP11A 抗体
    ATP11A (ATPase, Class VI, Type 11A (ATP11A))
    抗原表位
    N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 5
    克隆类型
    • 5
    多克隆
    标记
    • 5
    This ATP11A antibody is un-conjugated
    应用范围
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    19 amino acid peptide near the amino terminus of human ATP11A
    Top Product
    Discover our top product ATP11A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    ATP11A (ATPase, Class VI, Type 11A (ATP11A))
    别名
    ATP11A (ATP11A 产品)
    别名
    ATPIH antibody, ATPIS antibody, 4930558F19Rik antibody, AU040868 antibody, Atpc1h antibody, Ih antibody, Ua20 antibody, si:dkey-251i8.1 antibody, ATPase phospholipid transporting 11A antibody, ATPase, class VI, type 11A antibody, ATP11A antibody, Atp11a antibody, atp11a antibody
    背景
    ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.Synonyms: ATPIH, ATPIS, ATPase IS, ATPase class VI type 11A, KIAA1021, Probable phospholipid-transporting ATPase IH
    基因ID
    23250
    NCBI登录号
    NP_056020
    UniProt
    P98196
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