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VPS53 抗体 (Center)

VPS53 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783566
发货至: 中国
  • 抗原 See all VPS53 抗体
    VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))
    抗原表位
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Center
    适用
    • 21
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    • 2
    克隆类型
    • 21
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VPS53 antibody is un-conjugated
    应用范围
    • 14
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects VPS53 at Center.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid peptide from near the center of human VPS53
    Top Product
    Discover our top product VPS53 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))
    别名
    VPS53 (VPS53 产品)
    别名
    wu:fb77d11 antibody, zgc:103741 antibody, DKFZp469N152 antibody, 2010002A08Rik antibody, 2310040I21Rik antibody, 3100002B05Rik antibody, Hccs1 antibody, HCCS1 antibody, hVps53L antibody, pp13624 antibody, RGD1311391 antibody, VPS53, GARP complex subunit antibody, vacuolar protein sorting 53 homolog (S. cerevisiae) antibody, vacuolar protein sorting 53 antibody, VPS53 GARP complex subunit antibody, VPS53 antibody, vps53 antibody, PAAG_00802 antibody, MCYG_06020 antibody, VDBG_07188 antibody, MGYG_05943 antibody, Vps53 antibody
    背景
    The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist.Synonyms: PP13624, Vacuolar protein sorting-associated protein 53 homolog
    基因ID
    55275
    NCBI登录号
    NP_001121631
    UniProt
    Q5VIR6
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