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SLC7A11 抗体 (Internal Region)

SLC7A11 适用: 人, 犬 WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374804
发货至: 中国
  • 抗原 See all SLC7A11 抗体
    SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))
    抗原表位
    • 15
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 34
    • 15
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 犬
    宿主
    • 40
    • 1
    山羊
    克隆类型
    • 39
    • 2
    多克隆
    标记
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC7A11 antibody is un-conjugated
    应用范围
    • 34
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    C-KGQTQNFKDA FSGRD
    特异性
    This antibody detects XCT / SLC7A11.
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog).
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from the internal region of the protein sequence according to NP_055146.1 Genename: SLC7A11
    Top Product
    Discover our top product SLC7A11 Primary Antibody
  • 应用备注
    Peptide ELISA: antibody detection limit dilution 1: 128000. Western blot: Approx 50 kDa band observed in Human Spleen and Human Thymus lysates(calculated MW of 55.0 kDa according to NP_055146.1). Recommended concentration: 0.02-0.06 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))
    别名
    XCT / SLC7A11 (SLC7A11 产品)
    别名
    SLC7A11 antibody, DKFZp468E122 antibody, CCBR1 antibody, xCT antibody, 9930009M05Rik antibody, AI451155 antibody, sut antibody, solute carrier family 7 member 11 antibody, solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 antibody, SLC7A11 antibody, Slc7a11 antibody
    背景
    Mammalian amino acid transport systems consist of a large variety of transporters. The amino acid transporter, cystine/glutamic acid transporter xCT, for system xc has been proposed to be responsible for the cystine transport through the plasma membrane. System xc mediates an amino acid exchange and prefers cystine and glutamate as its substrates. The transporter designated as xCT requires 4F2 heavy chain (4F2hc:CD98) for its functional expression, and belongs to the family of amino acid transporters that associates with the type II membrane glycoproteins such as 4F2hc. In brain, it has been proposed that system xc is up-regulated in glial cells upon oxidative stress and plays an essential roles to protect neurons against oxidative stress. Recent studies have implicated xCT as a gateway that Kaposi's sarcoma herpesvirus (KSHV) uses to enter cells.Synonyms: Amino acid transport system xc, CCBR1, Calcium channel blocker resistance protein CCBR1, Cystine/glutamate transporter, Solute carrier family 7 member 11
    基因ID
    23657
    NCBI登录号
    NP_055146
    UniProt
    Q9UPY5
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