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CPT1A 抗体 (Internal Region)

CPT1A 适用: 人 WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374737
发货至: 中国
  • 抗原 See all CPT1A 抗体
    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
    抗原表位
    • 11
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 48
    • 18
    • 16
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 61
    • 4
    • 2
    山羊
    克隆类型
    • 62
    • 5
    多克隆
    标记
    • 32
    • 14
    • 10
    • 5
    • 3
    • 3
    This CPT1A antibody is un-conjugated
    应用范围
    • 62
    • 40
    • 23
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts to CPT1A. But is not expected to recognise CPT1B.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-DPAQTVEQRLKLFK, from the internal region of the protein sequence
    Top Product
    Discover our top product CPT1A Primary Antibody
  • 应用备注
    Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistryon paraffin sections: 4 - 6 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Patsoukis, Bardhan, Chatterjee, Sari, Liu, Bell, Karoly, Freeman, Petkova, Seth, Li, Boussiotis: "PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation." in: Nature communications, Vol. 6, pp. 6692, (2015) (PubMed).

  • 抗原
    CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
    别名
    CPT1A / CPT1-L (CPT1A 产品)
    别名
    MGC53498 antibody, CPT1 antibody, CPT1-L antibody, L-CPT1 antibody, L-CPTI antibody, si:dkey-56p7.8 antibody, C730027G07 antibody, CPTI antibody, Cpt1 antibody, CPT-Ia antibody, carnitine palmitoyltransferase 1A (liver) L homeolog antibody, carnitine palmitoyltransferase 1A antibody, carnitine palmitoyltransferase 1A (liver) antibody, carnitine palmitoyltransferase 1Aa (liver) antibody, carnitine palmitoyltransferase 1a, liver antibody, cpt1a.L antibody, CPT1A antibody, cpt1a antibody, cpt1aa antibody, Cpt1a antibody
    背景
    Carnitine palmitoyltransferase 1A (CPT1A) is involved in the mitochondrial oxidation of long chain fatty acids. The oxidation of long chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine acylcarnitine translocase. CPT I is the key enzyme in the carnitine dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta oxidation.Synonyms: Carnitine O-palmitoyltransferase 1 liver isoform, Carnitine palmitoyltransferase 1A
    基因ID
    1374, 9606
    UniProt
    P50416
    途径
    AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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