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SERPINI2 抗体 (Internal Region)

SERPINI2 适用: 人, 小鼠, 大鼠, 犬 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374538
发货至: 中国
  • 抗原 See all SERPINI2 抗体
    SERPINI2 (serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 (SERPINI2))
    抗原表位
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 42
    • 24
    • 20
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 39
    • 3
    • 2
    • 1
    山羊
    克隆类型
    • 44
    • 1
    多克隆
    标记
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERPINI2 antibody is un-conjugated
    应用范围
    • 44
    • 18
    • 13
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is expected to recognize both reported isoforms (NP_006208.1 and NP_001012303.1).
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine and (Dog).
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence C-KGDWKQKFRKEDTQ, from the internal region of the protein sequence. Genename: SERPINI2
    Top Product
    Discover our top product SERPINI2 Primary Antibody
  • 应用备注
    Peptide ELISA: Antibody detection limit dilution: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 40 kDa band observed in Human Pancreas lysates (calculated MW of 46.0 kDaaccording to NP_006208.1 and 47.0 kDa and NP_001012303.1). Immunohistochemistry on Paraffin Sections: 3 μg/mL. In paraffin embedded Human Pancreas, shows cytoplasmic staining of acinar cels and ofrare cells in the islets of Langerhans.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preserative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SERPINI2 (serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2 (SERPINI2))
    别名
    SERPINI2 (SERPINI2 产品)
    别名
    Spi14 antibody, MEPI antibody, PANCPIN antibody, PI14 antibody, TSA2004 antibody, serpin family I member 2 antibody, serpin peptidase inhibitor, clade I (pancpin), member 2 L homeolog antibody, serpin peptidase inhibitor, clade I (pancpin), member 2 antibody, serine (or cysteine) peptidase inhibitor, clade I, member 2 antibody, SERPINI2 antibody, serpini2.L antibody, Serpini2 antibody
    背景
    MEP1 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.Synonyms: MEPI, Myoepithelium-derived serine protease inhibitor, PI14, Pancpin, Protease inhibitor 14, TSA2004
    基因ID
    5276
    NCBI登录号
    NP_006208
    UniProt
    O75830
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