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CILP 抗体 (Internal Region)

CILP 适用: 人, 大鼠, 小鼠, 犬 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN453982
发货至: 中国
  • 抗原 See all CILP 抗体
    CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
    抗原表位
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 26
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 犬
    宿主
    • 20
    • 4
    • 2
    • 2
    山羊
    克隆类型
    • 25
    • 3
    多克隆
    标记
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CILP antibody is un-conjugated
    应用范围
    • 25
    • 14
    • 13
    • 13
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes CILP.
    交叉反应 (详细)
    Species reactivity (expected):Human, Mouse and Canine (Dog).
    Species reactivity (tested):Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence C-NYRRTDHEDPRVK, from the internal region of the protein sequence according to NP_003604.2.
    Top Product
    Discover our top product CILP Primary Antibody
  • 应用备注
    Peptide ELISA: Antibody Detection Limit Dilution: 1/128000. Western Blot: 0.1-0.3 μg/mL. Approx 150 kDa band observed in rat spinal cord lysates(calculated MW of 130 kDa according to human NP_003604.2 and of 130 kDa according toRat NP_001101631.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
    别名
    CILP1 (CILP 产品)
    别名
    CILP-1 antibody, HsT18872 antibody, 9830114D16 antibody, C130036G17Rik antibody, NTPPH antibody, CILP antibody, im:7137994 antibody, cartilage intermediate layer protein antibody, cartilage intermediate layer protein, nucleotide pyrophosphohydrolase antibody, cartilage intermediate layer protein 1 antibody, CILP antibody, Cilp antibody, cilp antibody, LOC100336614 antibody
    背景
    CILP, Cartilage Intermediate Layer Protein, is specifically expressed in the articular cartilage intermediate layer (it cannot be found in the superficial nor in the deepest layers) and is involved in scaffolding. Overexpression of this protein may lead to impairment of chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage. Antibodies against CILP are detected in patients with early-stage knee osteoarthritis and defects in this gene may be a cause of susceptibility to lumbar disk disease.Synonyms: CILP-1, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein
    基因ID
    8483
    NCBI登录号
    NP_003604
    UniProt
    O75339
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