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TRPC6 抗体 (C-Term)

TRPC6 适用: 人, Chimpanzee WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F2-H10-F2 unconjugated
产品编号 ABIN400824
发货至: 中国
  • 抗原 See all TRPC6 抗体
    TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
    抗原表位
    • 7
    • 6
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 26
    • 20
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Chimpanzee
    宿主
    • 23
    • 6
    • 2
    • 1
    小鼠
    克隆类型
    • 27
    • 5
    单克隆
    标记
    • 31
    • 1
    This TRPC6 antibody is un-conjugated
    应用范围
    • 25
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific for Human TRPC6 protein.
    交叉反应 (详细)
    Species reactivity (expected):Chimpanzee.
    Species reactivity (tested):Human.
    产品特性
    Synonyms: TRP-6, Short transient receptor potential channel 6
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6protein.
    克隆位点
    3F2-H10-F2
    亚型
    IgG1
    Top Product
    Discover our top product TRPC6 Primary Antibody
  • 应用备注
    Immunohistochemistry: 2.5 μg/mL. Western Blot: 1/500- 1/2000. ELISA: 1/10000 - 1/50000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
    别名
    TRPC6 (TRPC6 产品)
    背景
    TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or Gprotein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.Synonyms: Short transient receptor potential channel 6, TRP-6, Transient receptor protein 6
    基因ID
    7225
    UniProt
    Q9Y210
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