KDM5D 抗体 (C-Term)
KDM5D
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all KDM5D 抗体
- KDM5D (Lysine (K)-Specific Demethylase 5D (KDM5D))
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抗原表位
- AA 1248-1539, C-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDM5D antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects Human JARID1D. Other species not tested.
- 纯化方法
- Protein A Chromatography
- 免疫原
- Highly pure (> 95%) recombinant Human JARID1D (Leu1248-Leu1539) fused to a C-terminal His-tag (6x His) derived from E. coli (Cat.-No AR60001PU-N)
- 亚型
- IgG
- Top Product
- Discover our top product KDM5D Primary Antibody
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anti-Lysine (K)-Specific Demethylase 5D (KDM5D) (AA 127-230) antibody
KDM5D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Lysine (K)-Specific Demethylase 5D (KDM5D) (C-Term) antibodyKDM5D 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western blot: 1-5 μg/mL.
- 限制
- 仅限研究用
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- 缓冲液
- Purification: Protein A Chromatography
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
- 有效期
- 12 months
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- 抗原
- KDM5D (Lysine (K)-Specific Demethylase 5D (KDM5D))
- 别名
- jarid1d (KDM5D 产品)
- 别名
- JARID1D antibody, Jarid1d antibody, DKFZp468I1010 antibody, HY antibody, HYA antibody, SMCY antibody, Smcy antibody, lysine demethylase 5D antibody, lysine (K)-specific demethylase 5D antibody, lysine demethylase 5C antibody, KDM5D antibody, Kdm5d antibody, KDM5C antibody
- 背景
- H-Y antigen is defined as a male histocompatibility antigen that causes rejection of male skin grafts by female recipients of the same inbred strain of rodents. Male-specific, or H-Y antigen(s), are also detected by cytotoxic T cells and antibodies. H-Y antigen appears to be an integral part of the membrane of most male cells. In addition, H-Y antibodies detect a soluble form of H-Y that is secreted by the testis. The gene (Smcy/SMCY) coding for H-Y antigen detected by T cells has been cloned. It is expressed ubiquitously in male mice and humans, and encodes an epitope that triggers a specific T-cell response in vitro. Additional epitopes coded for by different Y-chromosomal genes are probably required in vivo for the rejection of male grafts by female hosts. The molecular nature of H-Y antigen detected by antibodies on most male cells is not yet known. Testis-secreted, soluble H-Y antigen, however, was found to be identical to Müllerian-inhibiting substance (MIS). MIS cross-reacts with H-Y antibodies and identical findings were obtained for soluble H-Y antigen and MIS, i.e., secretion by testicular Sertoli and, to a lesser degree, ovarian cells, binding to a gonad-specific receptor, induction of gonadal sex reversal in vitro and, in cattle, in vivo. H-Y antisera also detect a molecule or molecules associated with the heterogametic sex in non-mammalian vertebrates. Molecular data on this antigen or antigens are not yet available.
- 途径
- Warburg Effect
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