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IRS4 抗体 (AA 633-647)

Verified IRS4 适用: 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN5539610
发货至: 中国
  • 抗原 See all IRS4 抗体
    IRS4 (Insulin Receptor Substrate 4 (IRS4))
    抗原表位
    • 15
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 633-647
    适用
    • 31
    • 22
    • 15
    小鼠
    宿主
    • 36
    • 2
    山羊
    克隆类型
    • 36
    • 2
    多克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This IRS4 antibody is un-conjugated
    应用范围
    • 26
    • 26
    • 21
    • 10
    • 6
    • 6
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    原理
    Irs4 (mouse aa633-647)
    序列
    DRGTKERKEA KEVRD
    交叉反应
    小鼠, 大鼠
    纯化方法
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    质量等级
    Verified
    亚型
    IgG
    Top Product
    Discover our top product IRS4 Primary Antibody
  • 应用备注

    Western Blot: Approx 150 kDa band observed in Mouse Heart lysates (calculated MW of 130 kDa according to NP_034702.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Schreyer et al, jEndocrinology. 20

    Peptide ELISA: antibody detection limit dilution 1:128000.

    说明

    Immunofluorescence: This product has been successfully used in IF on Mouse: Harriet M Jackson et al, BMC Genomics. 2013 Nov 25,14:831. PMID: 24274089.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Minimize freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Ikink, Boer, Bakker, Hilkens: "IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation." in: Nature communications, Vol. 7, pp. 13567, (2018) (PubMed).

  • 抗原
    IRS4 (Insulin Receptor Substrate 4 (IRS4))
    别名
    Irs4 (IRS4 产品)
    别名
    IRS4 antibody, irs-4 antibody, py160 antibody, IRS-4 antibody, PY160 antibody, irs2 antibody, irs2-a antibody, insulin receptor substrate 4 antibody, insulin receptor substrate 4 S homeolog antibody, IRS4 antibody, irs4 antibody, Irs4 antibody, irs4.S antibody
    背景
    Irs4, insulin receptor substrate 4, IRS-4, RP23-415G1.3, phosphoprotein of 160 kDa, pp160
    基因ID
    16370, 315350
    NCBI登录号
    NP_034702
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