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UCHL5 抗体 (N-Term)

UCHL5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5537675
发货至: 中国
  • 抗原 See all UCHL5 抗体
    UCHL5 (Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))
    抗原表位
    • 10
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 56-87, N-Term
    适用
    • 60
    • 19
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    人, 小鼠
    宿主
    • 57
    • 5
    克隆类型
    • 58
    • 4
    多克隆
    标记
    • 36
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UCHL5 antibody is un-conjugated
    应用范围
    • 44
    • 25
    • 23
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This UCH37 (UCHL5) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-87 amino acids from the N-terminal region of human UCH37 (UCHL5).
    亚型
    Ig Fraction
    Top Product
    Discover our top product UCHL5 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    UCHL5 (Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))
    别名
    UCH37 (UCHL5 产品)
    别名
    zgc:85615 antibody, wu:fj17f09 antibody, uch37 antibody, cgi-70 antibody, DKFZp459M0513 antibody, 5830413B11Rik antibody, Uch37 antibody, CGI-70 antibody, INO80R antibody, UCH-L5 antibody, UCH37 antibody, ubiquitin carboxyl-terminal hydrolase L5 antibody, ubiquitin C-terminal hydrolase L5 antibody, ubiquitin C-terminal hydrolase L5 L homeolog antibody, ubiquitin carboxyl-terminal esterase L5 antibody, uchl5 antibody, UCHL5 antibody, uchl5.L antibody, Uchl5 antibody
    背景
    Covalent attachment of the C-terminus of ubiquitin to cellular proteins plays a role in a variety of cellular processes. Ubiquitin C-terminal hydrolysis is catalyzed by deubiquitinating (DUB) enzymes and is necessary for several functions, including liberation of monomeric ubiquitin from the precursors encoded by ubiquitin genes and recycling of ubiquitin monomers. There are 2 distinct families of DUBs, ubiquitin-specific proteases (UBPs) and ubiquitin C-terminal hydrolases (UCHs). Mayer and Wilkinson (1989) identified 4 distinct UCH activities from bovine thymus. All 4 were thiol proteases and had high-affinity binding sites for ubiquitin. Wilkinson et al. (1989) purified the predominant isozyme, UCHL3, and raised antibodies against it. By screening a human B-cell expression library with the antibodies, the authors isolated cDNAs encoding human UCHL3. Sequence comparisons revealed that the sequence of the predicted 230-amino acid human UCHL3 protein is 54 % identical to that of UCHL1.
    分子量
    38 kDa
    基因ID
    51377
    UniProt
    Q9Y5K5
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