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SETD8 抗体 (C-Term)

SETD8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5537415
发货至: 中国
  • 抗原 See all SETD8 抗体
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    抗原表位
    • 22
    • 8
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 362-393, C-Term
    适用
    • 64
    • 22
    • 11
    宿主
    • 48
    • 16
    克隆类型
    • 47
    • 17
    多克隆
    标记
    • 28
    • 8
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SETD8 antibody is un-conjugated
    应用范围
    • 51
    • 36
    • 23
    • 9
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This SET07 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 362-393 amino acids from the C-terminal region of human SET07.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SETD8 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    别名
    SET07 (SETD8 产品)
    别名
    KMT5A antibody, PR-Set7 antibody, SET07 antibody, SET8 antibody, 2410195B05Rik antibody, AA617402 antibody, AW536475 antibody, PR-SET7 antibody, setd8b antibody, wu:fc23f12 antibody, zgc:171649 antibody, Pr-set7 antibody, RGD1305893 antibody, Setd8 antibody, kmt5a antibody, kmt5a-a antibody, setd8 antibody, setd8-a antibody, set8a antibody, setd8a antibody, wu:fj33f02 antibody, zgc:153719 antibody, lysine methyltransferase 5A antibody, lysine methyltransferase 5Ab antibody, lysine methyltransferase 5A S homeolog antibody, lysine methyltransferase 5Aa antibody, KMT5A antibody, Kmt5a antibody, kmt5ab antibody, kmt5a.S antibody, kmt5aa antibody
    背景
    SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.
    分子量
    43 kDa
    基因ID
    387893
    UniProt
    Q9NQR1
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