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MLL/KMT2A 抗体 (C-Term)

MLL 适用: 人 IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5536269
发货至: 中国
  • 抗原 See all MLL/KMT2A (MLL) 抗体
    MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
    抗原表位
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3879-3908, C-Term
    适用
    • 31
    • 12
    • 9
    宿主
    • 26
    • 5
    克隆类型
    • 27
    • 4
    多克隆
    标记
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MLL/KMT2A antibody is un-conjugated
    应用范围
    • 17
    • 14
    • 14
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This HRX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3879-3908 amino acids from the C-terminal region of human HRX.
    亚型
    Ig Fraction
    Top Product
    Discover our top product MLL Primary Antibody
  • 应用备注
    For FACS starting dilution is: 1:10~50

    For IHC-P starting dilution is: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
    别名
    HRX (MLL 产品)
    别名
    ALL-1 antibody, CXXC7 antibody, HRX antibody, HTRX1 antibody, MLL antibody, MLL/GAS7 antibody, MLL1A antibody, TET1-MLL antibody, TRX1 antibody, WDSTS antibody, 6430520K01 antibody, All1 antibody, Cxxc7 antibody, Mll antibody, Mll1 antibody, mKIAA4050 antibody, lysine methyltransferase 2A antibody, lysine (K)-specific methyltransferase 2A antibody, KMT2A antibody, Kmt2a antibody
    背景
    The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. Tse et al. (1995) characterized 2 t(1,11)(q21,q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21, AF1Q, in 2 infants with acute myelomonocytic leukemia. In one of these patients, the derivative chromosome 11 represented an in-frame fusion of the N-terminal portion of the MLL gene to the complete AF1Q open reading frame, whereas the derivative chromosome 1 did not give rise to an open reading frame. This observation suggested that the N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23.
    分子量
    432 kDa
    基因ID
    4297
    UniProt
    Q03164
    途径
    Warburg Effect
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