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SULT1A1 抗体 (AA 128-160)

SULT1A1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5534723
发货至: 中国
  • 抗原 See all SULT1A1 抗体
    SULT1A1 (Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 (SULT1A1))
    抗原表位
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 128-160
    适用
    • 36
    • 20
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 32
    • 8
    克隆类型
    • 34
    • 6
    多克隆
    标记
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SULT1A1 antibody is un-conjugated
    应用范围
    • 32
    • 14
    • 11
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This SULT1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-160 amino acids from the Central region of human SULT1A1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SULT1A1 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SULT1A1 (Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 (SULT1A1))
    别名
    SULT1A1 (SULT1A1 产品)
    别名
    HAST1/HAST2 antibody, P-PST antibody, PST antibody, ST1A1 antibody, ST1A3 antibody, STP antibody, STP1 antibody, TSPST1 antibody, AI266890 antibody, Stp antibody, Stp1 antibody, ASTIV antibody, Mx-ST antibody, PST-1 antibody, St1a1 antibody, Stm antibody, Sult1a3 antibody, pst antibody, st1a3 antibody, stp antibody, stp1 antibody, tspst1 antibody, cSULT1A1 antibody, SULT1A2 antibody, SULT1A1 antibody, SIAT8-D antibody, ST8SiaIV antibody, Siat8d antibody, PST1 antibody, SIAT8D antibody, ST8SIA-IV antibody, sulfotransferase family 1A member 1 antibody, sulfotransferase family 1A, phenol-preferring, member 1 antibody, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 antibody, sulfotransferase family 1A member 1 S homeolog antibody, sulfotransferase 1A1 antibody, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 antibody, SULT1A1 antibody, Sult1a1 antibody, sult1a1 antibody, sult1a1.S antibody, LOC704658 antibody, LOC709318 antibody, St8sia4 antibody, ST8SIA4 antibody, LOC100064221 antibody
    背景
    Sulphation is a significant detoxification pathway for diverse xenobiotics, yet this modification also plays an important role in the metabolism and bioactivation of many dietary and environmental mutagens, including heterocyclic amines implicated in the pathogenesis of several cancers. A major human sulfotransferase, SULT1A1, metabolizes and/or bioactivates many endogenous compounds and is implicated in a range of cancers because of its ability to transform xenobiotics to cellular mutagens and carcinogens. Genetic polymorphisms in human sulfotransferase 1A1 SULT1A1 have a major impact on SULT1A1 enzyme activity and affect the risk for cancer development in humans. A G--->A transition at codon 213 (CGC/Arg to CAC/His) of the SULT1A1 gene has been identified (SULT1A1*2), and individuals homozygous for the His allele have a markedly lower activity and stability of this enzyme than those with the high activity SULT1A1*1 allozyme, which has been associated with protection against dietary toxins and reduced susceptibility to colorectal and breast cancers.There is an increasing incidence of SULT1A1*1 homozygosity and decreasing incidence of SULT1A1*2 homozygosity with increasing age, indicating a potential association of SULT1A1*1 allozyme(s) with protection against cell and/or tissue damage during aging. CLN3, the locus for Batten disease, maps to the same region 16p12.1-p11.2 as SULT12A1, making SULT1A1 a candidate gene for this disorder.
    分子量
    34 kDa
    基因ID
    6817
    UniProt
    P50225
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