电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

DERL1 抗体 (C-Term)

DERL1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5534194
发货至: 中国
  • 抗原 See all DERL1 抗体
    DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
    抗原表位
    • 15
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 224-251, C-Term
    适用
    • 39
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 38
    • 1
    克隆类型
    • 38
    • 1
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DERL1 antibody is un-conjugated
    应用范围
    • 23
    • 16
    • 13
    • 13
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DERL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the C-terminal region of human DERL1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product DERL1 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:2000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
    别名
    DERL1 (DERL1 产品)
    别名
    CG10908 antibody, Dmel\\CG10908 antibody, DDBDRAFT_0188135 antibody, DDBDRAFT_0266772 antibody, DDB_0188135 antibody, DDB_0266772 antibody, MGC84200 antibody, wu:fb09d07 antibody, wu:fb94d05 antibody, wu:fj92g12 antibody, zgc:55637 antibody, 1110021N07Rik antibody, AI195141 antibody, AW551338 antibody, Derlin-1 antibody, derlin-1 antibody, DER-1 antibody, DER1 antibody, RGD1311835 antibody, DERLIN-1 antibody, F17A13.150 antibody, F17A13_150 antibody, Derlin-1 antibody, derlin-1 antibody, derlin-1.1 antibody, hypothetical protein antibody, Der1-like domain family, member 1 antibody, derlin 1 antibody, derlin 1 L homeolog antibody, DERLIN-1 antibody, Der-1 antibody, EDI_023440 antibody, PTRG_01331 antibody, derl1 antibody, DERL1 antibody, derl1.L antibody, Derl1 antibody, DER1 antibody
    背景
    Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. DERL1 may act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. It may mediate the interaction between VCP and the degradation substrate. In case of infection by cytomegaloviruses, it plays a central role in the export from the ER and subsequent degradation of MHC class I heavy chains via its interaction with US11 viral protein, which recognizes and associates with MHC class I heavy chains. Also participates in the degradation process of misfolded cytomegalovirus US2 protein.
    分子量
    29 kDa
    基因ID
    79139
    UniProt
    Q9BUN8
    途径
    ER-Nucleus Signaling
You are here:
客服