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PRKAG3 抗体 (AA 148-178)

PRKAG3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5533704
发货至: 中国
  • 抗原 See all PRKAG3 抗体
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 148-178
    适用
    • 63
    • 12
    • 1
    人, 小鼠
    宿主
    • 55
    • 9
    • 1
    克隆类型
    • 56
    • 9
    多克隆
    标记
    • 24
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRKAG3 antibody is un-conjugated
    应用范围
    • 56
    • 33
    • 15
    • 13
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This PRKAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-178 amino acids from the Central region of human PRKAG3.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PRKAG3 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    别名
    PRKAG3 (PRKAG3 产品)
    别名
    Ampkg3 antibody, prkag3-a antibody, PRKAG3 antibody, AMPKG3 antibody, AMPKg3L antibody, AMPKg3S antibody, Amkg3 antibody, protein kinase AMP-activated non-catalytic subunit gamma 3 antibody, protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b antibody, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit antibody, Prkag3 antibody, PRKAG3 antibody, prkag3.S antibody, prkag3-b antibody
    背景
    PRKAG3 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
    分子量
    54 kDa
    基因ID
    53632
    UniProt
    Q9UGI9
    途径
    AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effect
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