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PPID 抗体 (AA 336-370)

PPID 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5533624
发货至: 中国
  • 抗原 See all PPID 抗体
    PPID (Peptidylprolyl Isomerase D (PPID))
    抗原表位
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 336-370
    适用
    • 57
    • 33
    • 29
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 52
    • 6
    • 1
    克隆类型
    • 56
    • 3
    多克隆
    标记
    • 40
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPID antibody is un-conjugated
    应用范围
    • 51
    • 15
    • 14
    • 13
    • 12
    • 12
    • 11
    • 8
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Cyclophilin D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 336-370 amino acids from the human region of human Cyclophilin D.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PPID Primary Antibody
  • 应用备注
    For FACS starting dilution is: 1:25

    For WB starting dilution is: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    PPID (Peptidylprolyl Isomerase D (PPID))
    别名
    Cyclophilin D (PPID 产品)
    别名
    PPID antibody, CYP-40 antibody, CYPD antibody, Cyp-40 antibody, CypD antibody, wu:fb18b07 antibody, zgc:86711 antibody, 4930564J03Rik antibody, Ppidl antibody, Ppif antibody, cyp-40 antibody, cypd antibody, peptidylprolyl isomerase D antibody, peptidylprolyl isomerase D (cyclophilin D) antibody, peptidylprolyl isomerase D (cyclophilin D) S homeolog antibody, PPID antibody, Ppid antibody, ppid antibody, ppid.S antibody
    背景
    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA- binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer, the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large- cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.
    分子量
    41 kDa
    基因ID
    5481
    UniProt
    Q08752
    途径
    Nuclear Hormone Receptor Binding
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