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HAS1 抗体 (AA 166-193)

HAS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5533232
发货至: 中国
  • 抗原 See all HAS1 抗体
    HAS1 (Hyaluronan Synthase 1 (HAS1))
    抗原表位
    • 16
    • 8
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 166-193
    适用
    • 50
    • 24
    • 23
    • 6
    • 6
    • 5
    • 2
    • 1
    宿主
    • 45
    • 6
    克隆类型
    • 45
    • 6
    多克隆
    标记
    • 18
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HAS1 antibody is un-conjugated
    应用范围
    • 26
    • 26
    • 20
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the Central region of human HAS1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product HAS1 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.3 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    HAS1 (Hyaluronan Synthase 1 (HAS1))
    别名
    HAS1 (HAS1 产品)
    别名
    dg42 antibody, Xhas1 antibody, HAS antibody, shas1 antibody, hyaluronan synthase 1 antibody, hyaluronan synthase 1 S homeolog antibody, has1 antibody, HAS1 antibody, Has1 antibody, has1.S antibody
    背景
    Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase.
    分子量
    65 kDa
    基因ID
    3036
    UniProt
    Q92839
    途径
    Glycosaminoglycan Metabolic Process
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