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STAM 抗体 (C-Term)

Name: STAM 抗体 (C-Term)
SKU: ABIN5533142
Availability: OutOfStock

STAM 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot analysis of anti-STAM Antibody in Hela cell line lysates (35ug/lane)

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

IHC

Western blot analysis of STAM using rabbit polyclonal STAM Antibody (P341) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the STAM gene.

3 images

产品编号 ABIN5533142

发货至: 中国

Datasheet as PDF

抗原 See all STAM 抗体

STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
抗原表位
8

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 326-356, C-Term
适用
44

19

9

4

4

4

3

2

2

2

1
人
宿主
41

5

1

1
兔
Compatible Secondaries
克隆类型
45

3
多克隆
标记
36

2

1

1

1

1

1

1

1

1

1

1
This STAM antibody is un-conjugated
应用范围
35

17

16

9

8

5

3

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

免疫原

This STAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-356 amino acids from the C-terminal region of human STAM.

亚型

Ig Fraction

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Discover our top product STAM Primary Antibody
anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 196-465) antibody
STAM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 199-466) antibody
STAM 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 1-403) antibody
STAM 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2B11-1G1 unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 199-464) antibody
STAM 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) antibody
STAM 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (C-Term) antibody
STAM 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (Center) antibody
STAM 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 1-30), (N-Term) antibody
STAM 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB4633 unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 326-356), (C-Term) antibody
STAM 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04604 unconjugated

anti-Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (AA 196-465) antibody
STAM 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated

应用备注

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

限制

仅限研究用
状态

Liquid

浓度

2 mg/mL

缓冲液

Supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

别名

STAM (STAM 产品)

别名

STAM-1 antibody, STAM1 antibody, wu:fv75b10 antibody, zgc:55725 antibody, RGD1564499 antibody, signal transducing adaptor molecule antibody, signal transducing adapter molecule 1 antibody, Signal transducing adapter molecule 1 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 antibody, STAM antibody, CpipJ_CPIJ003516 antibody, Tsp_03939 antibody, stam-1 antibody, Stam antibody, stam antibody

背景

Stimulation of cells with cytokines initiates a signal transduction cascade involving cytokine receptors, Janus kinases (JAKs) and signal transducers and activators of transcription (STATs). STAM for 'signal-transducing adaptor molecule, induced after stimulation of cells with cytokine IL2, is a component of signal transduction downstream of JAK3.1 Human STAM cDNA cloned from a T-cell cDNA library encodes a 540-amino acid protein precipitated by anti-phosphotyrosine. Northern blot analysis indicates that STAM is expressed as a 2.9-kb message in a wide variety of tissue and cell types. The STAM sequence contains a Src-homology 3 (SH3) domain and an immunoreceptor tyrosine-based activation motif (ITAM). It has been suggested that STAM acts as an adaptor molecule in signal transduction pathways from cytokine receptors.

分子量

59 kDa

基因ID

8027

UniProt

Q92783

途径

EGFR Signaling Pathway, EGFR Downregulation