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KLKB1 抗体 (C-Term)

KLKB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5533087
发货至: 中国
  • 抗原 See all KLKB1 抗体
    KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
    抗原表位
    • 14
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 508-537, C-Term
    适用
    • 55
    • 20
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 55
    • 4
    • 1
    • 1
    克隆类型
    • 55
    • 6
    多克隆
    标记
    • 31
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This KLKB1 antibody is un-conjugated
    应用范围
    • 37
    • 34
    • 12
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This KLKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-537 amino acids from the C-terminal region of human KLKB1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product KLKB1 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.47 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))
    别名
    KLKB1 (KLKB1 产品)
    别名
    KLK3 antibody, PPK antibody, APS antibody, Kal-3 antibody, Kal3 antibody, Klk3 antibody, PSA antibody, KALP15 antibody, Kalp1 antibody, KLKB1 antibody, DKFZp459J2015 antibody, klkb1 antibody, kallikrein B1 antibody, kallikrein B, plasma 1 antibody, plasma kallikrein antibody, Plasma kallikrein antibody, kallikrein B, plasma (Fletcher factor) 1 antibody, coagulation factor XI antibody, kallikrein B1 L homeolog antibody, KLKB1 antibody, Klkb1 antibody, CpipJ_CPIJ004042 antibody, CpipJ_CPIJ014955 antibody, CpipJ_CPIJ020108 antibody, VAA_02266 antibody, LOC100549617 antibody, klkb1 antibody, klkb1.L antibody
    背景
    Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
    分子量
    71 kDa
    基因ID
    3818
    UniProt
    P03952
    途径
    Complement System, Brown Fat Cell Differentiation
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