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MLL3 抗体 (N-Term)

KMT2C 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5532940
发货至: 中国
  • 抗原 See all MLL3 (KMT2C) products
    MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1142-1175, N-Term
    适用
    宿主
    • 10
    • 1
    克隆类型
    • 10
    • 1
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MLL3 antibody is un-conjugated
    应用范围
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1142-1175 amino acids from the N-terminal region of human MLL3.
    亚型
    Ig Fraction
  • 应用备注
    For IHC-P starting dilution is: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    MLL3 (KMT2C) (Histone-lysine N-methyltransferase 2C (KMT2C))
    别名
    MLL3 (KMT2C 产品)
    别名
    HALR antibody, MLL3 antibody, E330008K23Rik antibody, Mll3 antibody, mKIAA1506 antibody, lysine methyltransferase 2C antibody, lysine (K)-specific methyltransferase 2C antibody, KMT2C antibody, Kmt2c antibody
    背景
    Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
    分子量
    541 kDa
    基因ID
    58508
    UniProt
    Q8NEZ4
    途径
    Warburg Effect
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