SPHK1 抗体 (AA 286-315)
-
- 抗原 See all SPHK1 抗体
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
-
抗原表位
- AA 286-315
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SPHK1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SPHK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human SPHK1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SPHK1 Primary Antibody
-
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibody
SPHK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03621 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343) antibodySPHK1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 148-398) antibodySPHK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibodySPHK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 50-384) antibodySPHK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30), (N-Term) antibodySPHK1 适用: 人 WB 宿主: 兔 Polyclonal RB3619 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30) antibodySPHK1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 59-89) antibodySPHK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
For IHC-P starting dilution is: 1:25
For WB starting dilution is: 1:1000 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.36 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- 抗原
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
- 别名
- SPHK1 (SPHK1 产品)
- 别名
- CG1747 antibody, Dmel\\CG1747 antibody, SK1 antibody, Sphk1 antibody, SPHK1 antibody, F18E5.160 antibody, F18E5_160 antibody, sphingosine kinase 1 antibody, SPHK antibody, 1110006G24Rik antibody, Sk1 antibody, Spk1 antibody, Sphingosine kinase 1 antibody, sphingosine kinase 1 antibody, sphingosine kinase 1 L homeolog antibody, Sk1 antibody, SPHK1 antibody, sphk1.L antibody, Sphk1 antibody
- 背景
- Sphingosine Kinase (SphK) catalyzes the phosphorylation of the lipid sphingosine, creating the bioactive lipid sphingosine-1-phosphate (S1P). S1P subsequently signals through cell surface G protein-coupled receptors, as well as intracellularly, to modulate cell proliferation, survival, motility and differentiation. SphK is an important signaling enzyme which is activated by diverse agents, including growth factors that signal through receptor tyrosine kinases, agents activating G protein-coupled receptors, and immunoglobulin receptors. Two SphK isotypes, SphK-1 and SphK-2, have been cloned, and both isotypes are ubiquitously expressed. SphK-1 has been shown to mediate cell growth, prevention of apoptosis, and cellular transformation, and is upregulated in a variety of human tumors. In contrast, SphK-2 increases apoptosis, and may be responsible for phosphorylating and activating the immunosuppressive drug FTY720.
- 分子量
- 43 kDa
- 基因ID
- 8877
- UniProt
- Q9NYA1
- 途径
- VEGF Signaling
-
