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Paxillin 抗体 (AA 94-125)

Name: Paxillin 抗体 (AA 94-125)
SKU: ABIN5531903
Availability: OutOfStock

PXN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blot at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.

Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with PXN Antibody (Y118) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC

Western blot analysis of PXN using rabbit polyclonal PXN Antibody (Y118) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with PXN gene (Lane 2).

3 images

产品编号 ABIN5531903

发货至: 中国

Datasheet as PDF

抗原 See all Paxillin (PXN) 抗体

Paxillin (PXN)
抗原表位
32

25

17

16

11

9

8

7

7

7

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 94-125
适用
198

104

72

16

8

7

5

4

3

3

1

1

1

1

1
人
宿主
190

27

1
兔
Compatible Secondaries
克隆类型
176

42
多克隆
标记
121

10

8

8

8

8

8

8

6

6

4

4

4

4

4

2

2

2

1
This Paxillin antibody is un-conjugated
应用范围
166

67

41

40

37

28

27

25

18

14

14

6

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This PXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-125 amino acids from human PXN.

亚型

Ig Fraction

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anti-Paxillin (PXN) (AA 201-461) antibody
PXN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 347-578) antibody
PXN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 1-262) antibody
PXN 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 327-568) antibody
PXN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 456-472) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (pTyr118) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 1-262) antibody
PXN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (pSer83) antibody
PXN 适用: 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) antibody
PXN 适用: 人 WB, ELISA, IF, IP, ICC 宿主: 小鼠 Monoclonal M107 unconjugated

应用备注

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

Paxillin (PXN)

别名

PXN (PXN 产品)

别名

AW108311 antibody, AW123232 antibody, Pax antibody, CG18061 antibody, CG18576 antibody, CG31794 antibody, CT40481 antibody, CT42454 antibody, DPaxillin antibody, DPxn antibody, DPxn37 antibody, Dmel\\CG31794 antibody, Dpax antibody, DpaxA antibody, PDLP antibody, dPax antibody, pax antibody, wu:fw71f12 antibody, PXN antibody, LOC100220858 antibody, paxillin antibody, Paxillin antibody, paxillin S homeolog antibody, paxillin a antibody, PXN antibody, Pxn antibody, Pax antibody, pxn.S antibody, pxna antibody, LOC696336 antibody, pxn antibody

背景

PXN is a cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. PXN contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).

分子量

65 kDa

基因ID

5829

UniProt

P49023

途径

MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling