NFAT1 抗体 (AA 594-676)
(1 reference)-
- 抗原 See all NFAT1 抗体
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
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抗原表位
- AA 594-676
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFAT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Rabbit IgG polyclonal antibody for NFAT1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for NFAT1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: nuclear factor of activated T-cells 2
Protein Name: Nuclear factor of activated T-cells, cytoplasmic 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived huamn NFAT1 recombinant protein (Position: Q594-H676).
- 亚型
- IgG
- Top Product
- Discover our top product NFAT1 Primary Antibody
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anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) antibody
NFAT1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (N-Term) antibodyNFAT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (Internal Region) antibodyVerified NFAT1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (C-Term) antibodyNFAT1 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (C-Term) antibodyNFAT1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (AA 640-700) antibodyNFAT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (AA 210-440) antibodyNFAT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) antibodyNFAT1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (AA 812-921) antibodyNFAT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (AA 812-921) antibodyNFAT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A4 unconjugated
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- 应用备注
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Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "The protective effects of PCPA against monocrotaline-induced pulmonary arterial hypertension are mediated through the downregulation of NFAT-1 and NF-κB." in: International journal of molecular medicine, Vol. 40, Issue 1, pp. 155-163, (2018) (PubMed).
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: "The protective effects of PCPA against monocrotaline-induced pulmonary arterial hypertension are mediated through the downregulation of NFAT-1 and NF-κB." in: International journal of molecular medicine, Vol. 40, Issue 1, pp. 155-163, (2018) (PubMed).
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- 抗原
- NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
- 别名
- NFATC2 (NFAT1 产品)
- 别名
- NFATC2 antibody, AI607462 antibody, NF-ATc2 antibody, NFAT1 antibody, NFAT1-D antibody, Nfatp antibody, NFATP antibody, nuclear factor of activated T-cells 2 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 antibody, NFATC2 antibody, nfatc2 antibody, Nfatc2 antibody
- 背景
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NFATC2(Nuclear factor of activated T-cells, cytoplasmic 2), also known as NFATP or the 'preexisting component' of NFAT, is present in the cytosolic fraction of unstimulated T cells, which is also a member of the nuclear factor of activated T cells (NFAT) family. The NFATC2 gene is mapped on 20q13.2. NFATC2 is highly homologous to NFATC1 over a limited domain which shows similarity to the Dorsal/Rel family but has a wider tissue distribution. Ectopic expression of NFATC2 inhibited the basal activity of the human CDK4 promoter. Additionally, both Calna-/- and Nfatc2 -/- mice had elevated protein levels of Cdk4, confirming a negative regulatory role for the calcineurin/NFAT pathway. NFATC2 controls myoblast fusion at a specific stage of myogenesis after the initial formation of a myotube and is necessary for further cell growth. Overexpression of NFATC2 promoted differentiation of osteoclast precursor cells into tartrate-resistant acid phosphatase-positive (TRAP-positive) multinucleated osteoclast-like cells even in the absence of RANKL.
Synonyms: Nuclear factor of activated T-cells, cytoplasmic 2, NF-ATc2, NFATc2, NFAT pre-existing subunit, NF-ATp, T-cell transcription factor NFAT1, NFATC2, NFAT1, NFATP - 基因ID
- 4773
- UniProt
- Q13469
- 途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling
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