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CXCL12 抗体

Name: CXCL12 抗体
SKU: ABIN5518981
Availability: OutOfStock

CXCL12 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

Western blot analysis of SDF1 using anti-SDF1 antibody .

1 image

(8 references)

产品编号 ABIN5518981

发货至: 中国

Datasheet as PDF

抗原 See all CXCL12 抗体

CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
适用
67

23

19

3

2

1

1

1

1

1

1

1

1
小鼠, 大鼠
宿主
82

9

5

2
兔
Compatible Secondaries
克隆类型
85

13
多克隆
标记
44

16

6

4

3

3

3

3

3

3

2

2

1

1

1

1

1

1
This CXCL12 antibody is un-conjugated
应用范围
76

38

34

13

13

11

9

7

6

5

4

4

4

3

1

1
Western Blotting (WB)

原理

Rabbit IgG polyclonal antibody for SDF1 detection. Tested with WB in Mouse,Rat.

序列

RQVCIDPKLK WIQEYLEKAL NKRLKM

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for SDF1 detection. Tested with WB in Mouse,Rat.
Gene Name: chemokine (C-X-C motif) ligand 12
Protein Name: Stromal cell-derived factor 1

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence of mouse SDF1 (RQVCIDPKLKWIQEYLEKALNKRLKM).

亚型

IgG

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anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) antibody
CXCL12 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 23-89) antibody
CXCL12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-89) antibody
CXCL12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 31-80) antibody
CXCL12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-89) antibody
CXCL12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (C-Term) antibody
CXCL12 适用: 人, 小鼠, 犬, 小鸡, 非洲爪蟾, Bat, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) antibody
CXCL12 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 24-70) antibody
CXCL12 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (C-Term) antibody
CXCL12 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 23-89) antibody
CXCL12 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated

应用备注

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Zhang, Zhu, Huang, Cai, Zeng, Xu, Liu, Yuan, Lin: "iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration." in: PLoS ONE, Vol. 11, Issue 12, pp. e0167474, (2017) (PubMed).

Zheng, Wu, Yang, Huang, Chen, Gong, Fu, Lin, Tan: "Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells." in: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2425-2431, (2016) (PubMed).

Zhu, Sun, Tan, Xu, Dai, Wang, Fan, Zhou: "Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF‑1α expression in vivo." in: Molecular medicine reports, Vol. 10, Issue 2, pp. 585-92, (2015) (PubMed).

Zhang, Wang, Yue, Liu, Liu: "Construction of a CXCL12-KDEL fusion gene to inhibit head and neck squamous cell carcinoma metastasis by intracellular sequestration of CXCR4." in: BioMed research international, Vol. 2015, pp. 195828, (2015) (PubMed).

Zhang, Teng, Liu, Zhang, Liu: "Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 16, (2015) (PubMed).

Tong, Ding, Shen, Chen, Bian, Ma, Yao, Yang: "Mesenchymal stem cell transplantation enhancement in myocardial infarction rat model under ultrasound combined with nitric oxide microbubbles." in: PLoS ONE, Vol. 8, Issue 11, pp. e80186, (2013) (PubMed).

Zhao, Wang, Mao, Ma, Han, Zhao, Xu: "CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma." in: World journal of gastroenterology, Vol. 17, Issue 19, pp. 2389-96, (2011) (PubMed).

Zhang, Qi, Li, Zhang, Xu, Wang, Sun: "Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 27, pp. 62, (2009) (PubMed).
抗原

CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

别名

CXCL12 (CXCL12 产品)

别名

IRH antibody, PBSF antibody, SCYB12 antibody, SDF1 antibody, TLSF antibody, TPAR1 antibody, CINC-1 antibody, Gro1 antibody, Pbsf antibody, Scyb12 antibody, Sdf1 antibody, Tlsf antibody, Tpar1 antibody, Fsp antibody, KC antibody, Mgsa antibody, N51 antibody, Scyb1 antibody, gro antibody, sdf-1 antibody, sdf1 antibody, xSDF-1 antibody, SDF-1 antibody, cxcl12 antibody, sdf-1a antibody, sdf1a antibody, wu:fa55e10 antibody, wu:fc16h12 antibody, wu:fj84c02 antibody, C-X-C motif chemokine ligand 12 antibody, C-X-C motif chemokine ligand 1 antibody, chemokine (C-X-C motif) ligand 12 antibody, chemokine (C-X-C motif) ligand 1 antibody, C-X-C motif chemokine ligand 12 L homeolog antibody, chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) antibody, CXCL12 antibody, cxcl12 antibody, Cxcl1 antibody, Cxcl12 antibody, cxcl12.L antibody, cxcl12a antibody

背景

The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: Stromal cell-derived factor 1, SDF-1, hSDF-1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, IRH, hIRH, Pre-B cell growth-stimulating factor, PBSF, SDF-1-beta(3-72), SDF-1-alpha(3-67), CXCL12, SDF1, SDF1A, SDF1B

基因ID

20315

UniProt

P48061

途径

Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling