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- 抗原 See all RANBP2 抗体
- RANBP2 (RAN Binding Protein 2 (RANBP2))
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抗原表位
- AA 3018-3057, C-Term
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RANBP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for E3 SUMO-protein ligase RanBP2(RANBP2) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- EQLAVRFKTK EVADCFKKTF EECQQNLMKL QKGHVSLAAE
- 交叉反应 （详细）
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for E3 SUMO-protein ligase RanBP2(RANBP2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: RAN binding protein 2
Protein Name: E3 SUMO-protein ligase RanBP2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RanBP2 (3018-3057aa EQLAVRFKTKEVADCFKKTFEECQQNLMKLQKGHVSLAAE), different from the related mouse sequence by nine amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RANBP2 Primary Antibody
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anti-RAN Binding Protein 2 (RANBP2) antibody
RANBP2 适用: 人, 小鼠, 大鼠 ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 2 (RANBP2) (AA 2601-2802) antibodyRANBP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 2 (RANBP2) antibodyRANBP2 适用: 人 WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 2 (RANBP2) (AA 1050-1100) antibodyRANBP2 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- RANBP2 (RAN Binding Protein 2 (RANBP2))
- 别名
- RANBP2 (RANBP2 产品)
- 别名
- ANE1 antibody, IIAE3 antibody, NUP358 antibody, TRP1 antibody, TRP2 antibody, A430087B05Rik antibody, AI256741 antibody, RGD1560047 antibody, RANBP2 antibody, ane1 antibody, nup358 antibody, trp1 antibody, trp2 antibody, RAN binding protein 2 antibody, E3 SUMO-protein ligase RanBP2 antibody, RANBP2 antibody, Ranbp2 antibody, LOC474539 antibody, ranbp2 antibody, LOC100511376 antibody
- 背景
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RAN binding protein 2 (RANBP2) is protein which in humans is encoded by the RANBP2 gene. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. And the encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q.
Synonyms: E3 SUMO-protein ligase RanBP2, 358 kDa nucleoporin, Nuclear pore complex protein Nup358, Nucleoporin Nup358, Ran-binding protein 2, RanBP2, p270, RANBP2, NUP358 - 基因ID
- 5903
- UniProt
- P49792
- 途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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