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PPARG 抗体 (Middle Region)

Name: PPARG 抗体 (Middle Region)
SKU: ABIN5518944
Availability: OutOfStock

PPARG 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

Western blot analysis of PPAR gamma using anti-PPAR gamma antibody .

1 image

(6 references)

产品编号 ABIN5518944

发货至: 中国

Datasheet as PDF

抗原 See all PPARG 抗体

PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
抗原表位
21

18

16

16

16

14

9

5

4

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 207-248, Middle Region
适用
155

108

95

34

33

24

22

20

15

10

6

6

5

3

3

2

2

2

1

1

1
人, 小鼠, 大鼠
宿主
147

18

3

2
兔
Compatible Secondaries
克隆类型
152

19
多克隆
标记
84

14

11

7

5

4

4

4

4

4

4

4

4

4

4

4

2

2

2
This PPARG antibody is un-conjugated
应用范围
153

60

55

52

52

31

22

16

14

13

7

5

5

4

2

1
Western Blotting (WB)

原理

Rabbit IgG polyclonal antibody for Peroxisome proliferator-activated receptor gamma(PPARG) detection. Tested with WB in Human,Mouse,Rat.

序列

AIRFGRMPQA EKEKLLAEIS SDIDQLNPES ADLRALAKHL YD

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Peroxisome proliferator-activated receptor gamma(PPARG) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: peroxisome proliferator activated receptor gamma
Protein Name: Peroxisome proliferator-activated receptor gamma

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human PPAR gamma (207-248aa AIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYD), identical to the related mouse and rat sequences.

亚型

IgG

Top Product

Discover our top product PPARG Primary Antibody
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 50-150) antibody
PPARG 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 101-200) antibody
PPARG 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 315-420) antibody
PPARG 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 149-273) antibody
PPARG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer273) antibody
PPARG 适用: 人, 小鼠, 大鼠, 绵羊, 豚鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 70-170) antibody
PPARG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) antibody
PPARG 适用: 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal 6D7B9 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Yang, Fu, Hu, Luo, Hu, Wang: "PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis." in: Experimental & molecular medicine, Vol. 50, Issue 1, pp. e431, (2018) (PubMed).

Wu, Wu, Jiao, Wang, Wang, Zhang: "Rosiglitazone infusion therapy following minimally invasive surgery for intracerebral hemorrhage evacuation decreases matrix metalloproteinase-9 and blood-brain barrier disruption in rabbits." in: BMC neurology, Vol. 15, pp. 37, (2016) (PubMed).

Chen, Bai, Liao, Peng, Wu, Wang, Zeng, Xie: "Electrospun poly(L-lactide)/poly(?-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71265, (2013) (PubMed).

Wang, Liu, Dang, Ma, Zhang, Wang: "The effect of core decompression on local expression of BMP-2, PPAR-γ and bone regeneration in the steroid-induced femoral head osteonecrosis." in: BMC musculoskeletal disorders, Vol. 13, pp. 142, (2012) (PubMed).

Xie, Wang, Zhang, Li, Can, Qing, Kung, Zhang: "Enhanced peroxisomal ?-oxidation metabolism in visceral adipose tissues of high-fat diet-fed obesity-resistant C57BL/6 mice." in: Experimental and therapeutic medicine, Vol. 2, Issue 2, pp. 309-315, (2012) (PubMed).

Xie, Zhao, Gu, Du, Cai, Zhang: "Scorpion in Combination with Gypsum: Novel Antidiabetic Activities in Streptozotocin-Induced Diabetic Mice by Up-Regulating Pancreatic PPARγ and PDX-1 Expressions." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2011, pp. 683561, (2011) (PubMed).
抗原

PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

别名

PPARG (PPARG 产品)

别名

PPAR gamma antibody, PPARg2 antibody, PPARG antibody, Nr1c3 antibody, PPAR-gamma antibody, PPAR-gamma2 antibody, PPARgamma antibody, PPARgamma2 antibody, NR1C3 antibody, CIMT1 antibody, GLM1 antibody, PPARG1 antibody, PPARG2 antibody, xPPAR-gamma antibody, PPAR-GAMMA antibody, PPARGAMMA antibody, peroxisome proliferator-activated receptor gamma antibody, peroxisome proliferator activated receptor gamma antibody, peroxisome proliferator activated receptor gamma L homeolog antibody, PPARG antibody, Pparg antibody, pparg.L antibody

背景

The peroxisome proliferator-activated receptors (PPARs) are a group of three nuclear receptor isoforms, PPAR gamma, PPAR alpha, and PPAR delta, encoded by different genes. PPARs are ligand-regulated transcription factors that control gene expression by binding to specific response elements (PPREs) within promoters. PPAR gamma is a transcription factor that has a pivotal role in adipocyte differentiation and expression of adipocyte-specific genes. The PPAR gamma1 and gamma2 isoforms result from alternative splicing and have ligand-dependent and -independent activation domains. PPAR gamma is a member of a family of nuclear receptors/ligand-dependent transcription factors, which bind to hormone response elements on target gene promoters. PPAR gamma is abundantly expressed in normal lung tissues, especially in endothelial cells, but that its expression is reduced or absent in the angiogenic plexiform lesions of pulmonary hypertensive lungs and in the vascular lesions of a rat model of severe pulmonary hypertension. And it is concluded that fluid shear stress decreases the expression of PPARgamma in endothelial cells and that loss of PPARgamma expression characterizes an abnormal, proliferating, apoptosis-resistant endothelial cell phenotype.

Synonyms: Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG, NR1C3

基因ID

5468

UniProt

P37231

途径

MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation