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ABCG8 抗体 (Middle Region)

ABCG8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518720
发货至: 中国
  • 抗原 See all ABCG8 抗体
    ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
    抗原表位
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 328-371, Middle Region
    适用
    人, 小鼠, 大鼠
    宿主
    • 26
    克隆类型
    • 26
    多克隆
    标记
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCG8 antibody is un-conjugated
    应用范围
    • 15
    • 11
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 8(ABCG8) detection. Tested with WB in Human,Mouse,Rat.
    序列
    DRRSREQELA TREKAQSLAA LFLEKVRDLD DFLWKAETKD LDED
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 8(ABCG8) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: ATP binding cassette subfamily G member 8
    Protein Name: ATP-binding cassette sub-family G member 8
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human ABCG8 (328-371aa DRRSREQELATREKAQSLAALFLEKVRDLDDFLWKAETKDLDED), different from the related mouse and rat sequences by twelve amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ABCG8 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
    别名
    ABCG8 (ABCG8 产品)
    别名
    DDBDRAFT_0167690 antibody, DDBDRAFT_0191232 antibody, DDB_0167690 antibody, DDB_0191232 antibody, zgc:172358 antibody, GBD4 antibody, STSL antibody, 1300003C16Rik antibody, AI114946 antibody, sterolin-2 antibody, ATP binding cassette subfamily G member 8 antibody, ATP-binding cassette sub-family G member 8 antibody, ABC transporter G family protein antibody, ATP-binding cassette, sub-family G (WHITE), member 8 antibody, ABCG8 antibody, PTRG_02054 antibody, abcG8 antibody, abcg8 antibody, Abcg8 antibody
    背景
    ATP-binding cassette sub-family G member 8 is a protein that in humans is encoded by the ABCG8 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

    Synonyms: ABCG8 | GBD4 | Sterolin 2 | Sterolin-2 | TSL | Q9H221
    基因ID
    64241
    UniProt
    Q9H221
    途径
    Lipid Metabolism
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