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- 抗原 See all ABCA4 抗体
- ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
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抗原表位
- AA 1890-1927, C-Term
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABCA4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Retinal-specific ATP-binding cassette transporter(ABCA4) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- FLLTLLVQRH FFLSQWIAEP TKEPIVDEDD DVAEERQR
- 交叉反应 （详细）
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Retinal-specific ATP-binding cassette transporter(ABCA4) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 4
Protein Name: Retinal-specific ATP-binding cassette transporter - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ABCA4 (1890-1927aa FLLTLLVQRHFFLSQWIAEPTKEPIVDEDDDVAEERQR), different from the related mouse sequence by eight amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ABCA4 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 2250-2263) antibody
Verified ABCA4 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 1398-1727) antibodyABCA4 适用: 人 WB, ELISA, IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) antibodyABCA4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 2174-2273) antibodyABCA4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (C-Term) antibodyABCA4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) antibodyABCA4 适用: Cow WB, IHC 宿主: 小鼠 Monoclonal 3F4 unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
- 别名
- ABCA4 (ABCA4 产品)
- 背景
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ABCA4 (ATP-Binding Cassette, Subfamily A, Member 4), also known as ABCR, is a protein which in humans is encoded by the ABCA4 gene. ABCA4 is a member of the ATP-binding cassette transporter gene sub-family A (ABC1) found exclusively in multicellular eukaryotes. Using a whole genome radiation hybrid panel, this gene is mapped to 1p21-p13. And this gene is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Additionally, it is showed by immunofluorescence microscopy and Western blot analysis that ABCR is present in foveal and peripheral cone, as well as rod, photoreceptors. The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCR-mediated foveal cone degeneration.
Synonyms: ABCA 4 | ABCA4 | ABCR | ARMD 2 | ARMD2 | ATP binding cassette 10 | CORD3 | FFM | P78363 | Photoreceptor rim protein | RIM ABC transporter | RIM protein | RmP | RP19 | Stargardt disease protein | STGD | STGD1 - 基因ID
- 24
- UniProt
- P78363
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