KDM5B 抗体 (C-Term)
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- 抗原 See all KDM5B 抗体
- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDM5B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EMKKFPDNDL LRHLRLVTQD AEKCASVAQQ LLNGKRQTRY RSGGGKSQNQ
- 产品特性
- This is a rabbit polyclonal antibody against KDM5B. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human KDM5B
- Top Product
- Discover our top product KDM5B Primary Antibody
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anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibody
KDM5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7H3D7 unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 65-165) antibodyKDM5B 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 231-319) antibodyKDM5B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) (AA 784-883) antibodyKDM5B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5B (KDM5B) antibodyKDM5B 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
- 别名
- KDM5B (KDM5B 产品)
- 别名
- jarid1b antibody, jarid1ba antibody, id:ibd5050 antibody, wu:fd15c05 antibody, cb264 antibody, jarid1bb antibody, plu1 antibody, wu:fc44h11 antibody, zgc:85741 antibody, JARID1B antibody, CT31 antibody, PLU-1 antibody, PLU1 antibody, PUT1 antibody, RBBP2H1A antibody, 2010009J12Rik antibody, 2210016I17Rik antibody, AW556288 antibody, D1Ertd202e antibody, Jarid1b antibody, Plu1 antibody, Rb-Bp2 antibody, mKIAA4034 antibody, RGD1565602 antibody, lysine (K)-specific demethylase 5Ba antibody, lysine (K)-specific demethylase 5Bb antibody, lysine demethylase 5B antibody, lysine (K)-specific demethylase 5B antibody, kdm5ba antibody, kdm5bb antibody, KDM5B antibody, Kdm5b antibody
- 背景
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KDM5B is a histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. KDM5B demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. It acts as a transcriptional corepressor for FOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor for melanoma.
Alias Symbols: KDM5B, JARID1B, PLU1, RBBP2H1,
Protein Interaction Partner: FBXW11, UBC, HDAC2, HDAC4, SUMO1, SUMO3, PPP1CA, TFAP2C, MYC, HDAC7, HDAC5, NCOR1, PAX9, HDAC1, ELAVL1, CHD3, MTA3, MBD3, KDM1A, MTA2, MBD2, RBBP7, RBBP4, RB1, SUMO2, KLF10, LMO2, FOXG1, AR, VGLL3, PRDM13, ARID1B, BMP2K, RNF43, RBM15B, DBNL, CECR6, SLC39A
Protein Size: 1544 - 基因ID
- 10765
- NCBI登录号
- NP_006609
- UniProt
- Q9UGL1
- 途径
- Warburg Effect
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