DJ6 antibody, 1700016F14Rik antibody, 1700031F10Rik antibody, AI326313 antibody, mDj6 antibody, DnaJ heat shock protein family (Hsp40) member B8 antibody, DNAJB8 antibody, Dnajb8 antibody
背景
The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma.