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- 抗原 See all KIDINS220 抗体
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIDINS220 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VERVPKSPEH SAEPIRTFIK AKEYLSDALL DKKDSSDSGV RSSESSPNHS
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 93%
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human KIDINS220
- Top Product
- Discover our top product KIDINS220 Primary Antibody
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anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (Internal Region) antibody
KIDINS220 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (C-Term) antibodyKIDINS220 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (pSer918) antibodyKIDINS220 适用: 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (AA 1335-1348), (C-Term), (Intracellular) antibodyKIDINS220 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
- 别名
- KIDINS220 (KIDINS220 产品)
- 背景
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Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
Alias Symbols: ARMS
Protein Interaction Partner: UBC, LGR4, MYC, FN1, MOB4, CDC73, PRKD1, CRKL, NTRK2, NTRK3, NTRK1, NGFR,
Protein Size: 59 - 分子量
- 543 kDa
- 基因ID
- 57498
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