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TAB2 抗体 (Middle Region)
TAB2
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
TAB2抗体详情
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抗原
See all TAB2 抗体
TAB2
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
抗原表位
All epitopes for TAB2 抗体
Middle Region
适用
All reactivities for TAB2 抗体
人
宿主
All hosts for TAB2 抗体
兔
克隆类型
All clonalities for TAB2 抗体
多克隆
标记
All conjugates for TAB2 抗体
This TAB2 antibody is un-conjugated
应用范围
All applications for TAB2 抗体
Western Blotting (WB)
序列
SGSSQSSAHS QYNIQNISTG PRKNQIEIKL EPPQRNNSSK LRSSGPRTSS
产品特性
This is a rabbit polyclonal antibody against TAB2. It was validated on Western Blot.
纯化方法
Affinity Purified
免疫原
The immunogen is a synthetic peptide directed towards the middle region of Human TAB2
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Discover our top product TAB2 Primary Antibody
Alternatives
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibody
TAB2
适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Pig, Bat, Hamster, 猴
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
TAB2目标详情
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抗原
TAB2
(TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
别名
TAB2 (TAB2 产品 )
别名
CHTD2 antibody, MAP3K7IP2 antibody, 1110030N06Rik antibody, A530078N03Rik antibody, Map3k7ip2 antibody, mKIAA0733 antibody, map3k7ip2 antibody, zgc:77446 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 2 antibody, TAB2 antibody, Tab2 antibody, tab2 antibody
背景
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. Alias Symbols: TAB2, KIAA0733, MAP3K7IP2, Protein Interaction Partner: UBC, PIAS3, UBE2I, TRAF6, SUMO2, IRAK1, MAP3K7, TRIM38, SIK1, SIK3, TRIM22, NPM1, CST9L, SLC19A3, env, TAB1, NUMBL, IKBKG, FOSL1, ZBTB16, YWHAZ, VIM, TGM2, PPP2CB, IKBKB, GTF2I, FN1, HSP90AA1, BST2, MALT1, WDR34, APP, ESR1, MAP3K8, AR, TRIM5, TBL1XR1, MBD Protein Size: 536
基因ID
23118
途径
TCR Signaling , TLR signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades , Ubiquitin Proteasome Pathway
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