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ATG14 抗体 (Middle Region)

ATG14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5516479
发货至: 中国
  • 抗原 See all ATG14 抗体
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 47
    • 15
    • 8
    • 1
    宿主
    • 39
    • 8
    克隆类型
    • 39
    • 8
    多克隆
    标记
    • 19
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ATG14 antibody is un-conjugated
    应用范围
    • 27
    • 22
    • 17
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    NEEMEKNSEG LLKTKEKNQK LYSRAQRHQE KKEKIQRHNR KLGDLVEKKT
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human ATG14
    Top Product
    Discover our top product ATG14 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    别名
    ATG14 (ATG14 产品)
    别名
    ATG14L antibody, BARKOR antibody, KIAA0831 antibody, 4832427M01 antibody, Atg14L antibody, D14Ertd114e antibody, D14Ertd436e antibody, RGD1304610 antibody, autophagy related 14 antibody, ATG14 antibody, Atg14 antibody
    背景
    Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1. Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK. Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion. Modulates the hepatic lipid metabolism.

    Alias Symbols: ATG14L, BARKOR, KIAA0831

    Protein Size: 492
    基因ID
    22863
    NCBI登录号
    NM_014924, NP_055739
    UniProt
    Q6ZNE5
    途径
    Autophagy
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