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EHD3 抗体 (N-Term)

EHD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5516009
发货至: 中国
  • 抗原 See all EHD3 抗体
    EHD3 (EH-Domain Containing 3 (EHD3))
    抗原表位
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 26
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 23
    • 3
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EHD3 antibody is un-conjugated
    应用范围
    • 15
    • 12
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    序列
    FSWLGTDDRR RKDPEVFQTV SEGLKKLYKS KLLPLEEHYR FHEFHSPALE
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human EHD3
    Top Product
    Discover our top product EHD3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    EHD3 (EH-Domain Containing 3 (EHD3))
    别名
    EHD3 (EHD3 产品)
    别名
    PAST3 antibody, Ehd2 antibody, EHD3 antibody, si:ch211-147c1.2 antibody, MGC146452 antibody, EH domain containing 3 antibody, EH-domain containing 3 antibody, EH domain containing 3 L homeolog antibody, EHD3 antibody, Ehd3 antibody, ehd3 antibody, ehd3.L antibody
    背景
    ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 dopamine receptor. Plays a role in cardiac protein trafficking probably implicating ANK. Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction. In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function. Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis, possibly sharing redundant functions with EHD1.

    Alias Symbols: PAST3

    Protein Size: 535
    基因ID
    30845
    NCBI登录号
    NM_014600, NP_055415
    UniProt
    Q9NZN3
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