DHCR7 抗体 (N-Term)
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- 抗原 See all DHCR7 抗体
- DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DHCR7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AAKSQPNIPK AKSLDGVTND RTASQGQWGR AWEVDWFSLA SVIFLLLFAP
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DHCR7
- Top Product
- Discover our top product DHCR7 Primary Antibody
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anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 437-463), (C-Term) antibody
DHCR7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17942 unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 1-475) antibodyDHCR7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 63-147) antibodyDHCR7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 351-450) antibodyDHCR7 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
- 别名
- DHCR7 (DHCR7 产品)
- 别名
- 7-Dhcr antibody, Xdhcr7 antibody, MGC64361 antibody, slos antibody, 7-STEROL DELTA7 REDUCTASE antibody, 7RED antibody, DELTA5 antibody, DWARF 5 antibody, F11F12.21 antibody, F11F12_21 antibody, LE antibody, LEPIDA antibody, PA antibody, PARVA antibody, ST7R antibody, STEROL DELTA7 REDUCTASE antibody, DKFZp468C1911 antibody, AA409147 antibody, SLOS antibody, xdhcr7 antibody, 7-dehydrocholesterol reductase antibody, 7-dehydrocholesterol reductase L homeolog antibody, Ergosterol biosynthesis ERG4/ERG24 family antibody, DHCR7 antibody, dhcr7 antibody, dhcr7.L antibody, DWF5 antibody, PAAG_04766 antibody, PITG_13128 antibody, VDBG_05423 antibody, MGYG_00712 antibody, TERG_00580 antibody, Dhcr7 antibody
- 背景
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This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS), a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.
Alias Symbols: SLOS
Protein Size: 475 - 基因ID
- 1717
- NCBI登录号
- NM_001163817, NP_001157289
- UniProt
- Q9UBM7
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