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Desmocollin 3 抗体 (Middle Region)

DSC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514719
发货至: 中国
  • 抗原 See all Desmocollin 3 (DSC3) 抗体
    Desmocollin 3 (DSC3)
    抗原表位
    • 9
    • 8
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 47
    • 33
    • 21
    • 6
    • 5
    • 1
    • 1
    • 1
    宿主
    • 44
    • 3
    • 1
    • 1
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 16
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmocollin 3 antibody is un-conjugated
    应用范围
    • 44
    • 19
    • 13
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    IKENLAVGSK INGYKAYDPE NRNGNGLRYK KLHDPKGWIT IDEISGSIIT
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human DSC3
    Top Product
    Discover our top product DSC3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Desmocollin 3 (DSC3)
    别名
    DSC3 (DSC3 产品)
    别名
    CDHF3 antibody, DSC antibody, DSC1 antibody, DSC2 antibody, DSC4 antibody, HT-CP antibody, 5430426I24Rik antibody, MGC85083 antibody, desmocollin 3 antibody, desmocollin 3 S homeolog antibody, DSC3 antibody, Dsc3 antibody, dsc3.S antibody, dsc3 antibody
    背景
    The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.

    Alias Symbols: DSC, DSC1, DSC2, DSC4, CDHF3, HT-CP,

    Protein Size: 839
    基因ID
    1825
    NCBI登录号
    NM_001941, NP_001932
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