DIO2 抗体 (Middle Region)
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- 抗原 See all DIO2 抗体
- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DIO2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ILLKHVVLLL SRSKSTRGEW RRMLTSEGLR CVWKSFLLDA YKQVKLGEDA
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human DIO2
- Top Product
- Discover our top product DIO2 Primary Antibody
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anti-Deiodinase, Iodothyronine, Type II (DIO2) (Internal Region) antibody
Verified DIO2 适用: 人, 小鼠 ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 165-191) antibodyDIO2 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22907 unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 74-222) antibodyDIO2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 165-191) antibodyDIO2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 101-200) antibodyDIO2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) antibodyDIO2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 30-259) antibodyDIO2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) antibodyDIO2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deiodinase, Iodothyronine, Type II (DIO2) (AA 171-200), (Middle Region) antibodyDIO2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
- 别名
- DIO2 (DIO2 产品)
- 别名
- 5DII antibody, D2 antibody, DIOII antibody, SelY antibody, TXDI2 antibody, AI324267 antibody, Deio2 antibody, cb684 antibody, DIO2 antibody, dio2-A antibody, 5dii antibody, sely antibody, txdi2 antibody, iodothyronine deiodinase 2 antibody, deiodinase, iodothyronine, type II antibody, deiodinase, iodothyronine, type 2 L homeolog antibody, deiodinase, iodothyronine, type 2 antibody, type II iodothyronine deiodinase antibody, DIO2 antibody, Dio2 antibody, dio2 antibody, dio2.L antibody, LOC100861220 antibody
- 背景
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The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: D2, 5DII, SelY, DIOII, TXDI2,
Protein Size: 273 - 基因ID
- 1734
- NCBI登录号
- NM_000793, NP_000784
- UniProt
- Q92813
- 途径
- Hormone Transport, Hormone Activity
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