电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NEDD8 抗体 (N-Term)

NEDD8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN542757
发货至: 中国
  • 抗原 See all NEDD8 抗体
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    抗原表位
    • 15
    • 8
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 62
    • 29
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 59
    • 4
    • 4
    克隆类型
    • 55
    • 12
    多克隆
    标记
    • 31
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEDD8 antibody is un-conjugated
    应用范围
    • 34
    • 22
    • 22
    • 13
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic peptide of NEDD8.
    交叉反应
    免疫原
    A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NEDD8.
    Top Product
    Discover our top product NEDD8 Primary Antibody
  • 应用备注
    Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In PBS (0.09 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Fan, Bigsby, Nephew et al.: "The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 17, Issue 3, pp. 356-65, (2003) (PubMed).

    Bohnsack, Haas: "Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer." in: The Journal of biological chemistry, Vol. 278, Issue 29, pp. 26823-30, (2003) (PubMed).

    Wu, Yamoah, Dolios, Gan-Erdene, Tan, Chen, Lee, Wei, Wilkinson, Wang, Pan: "DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1." in: The Journal of biological chemistry, Vol. 278, Issue 31, pp. 28882-91, (2003) (PubMed).

  • 抗原
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    别名
    NEDD8 (NEDD8 产品)
    别名
    NEDD-8 antibody, Rub1 antibody, CG10679 antibody, Dmel\\CG10679 antibody, NEDD8 antibody, dNEDD8 antibody, nedd8 antibody, ubiquitin antibody, si:zc14a17.5 antibody, GB17785 antibody, DDBDRAFT_0218116 antibody, DDBDRAFT_0238041 antibody, DDB_0218116 antibody, DDB_0238041 antibody, nedd8.S antibody, neural precursor cell expressed, developmentally down-regulated 8 antibody, neural precursor cell expressed, developmentally down-regulated gene 8 antibody, CG10679 gene product from transcript CG10679-RB antibody, Nedd8 antibody, ubiquitin-like protein Nedd8 antibody, neural precursor cell expressed, developmentally down-regulated 8 L homeolog antibody, NEDD8 antibody, Nedd8 antibody, nedd8 antibody, nedd8.L antibody
    基因ID
    4738
    途径
    Ubiquitin Proteasome Pathway
You are here:
客服