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- 抗原 See all PUMA (BBC3) 抗体
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PUMA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit polyclonal antibody raised against synthetic peptide of BBC3.
- 特异性
- This sequence is identical between a and b forms of the PUMA proteins. K-562 cell lysate can be used as a positive control and a band at approximately 23 KDa can be detected. antibody can also detect PUMA by immunohistochemistry at 10 μg/mL.
- 交叉反应
- 人
- 免疫原
- A synthetic peptide corresponding to N-terminus 14 amino acids of human BBC3.
- Top Product
- Discover our top product BBC3 Primary Antibody
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- 应用备注
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Western Blot (2-4 μg/mL)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In PBS (0.02 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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PUMA induces the rapid apoptosis of colorectal cancer cells." in: Molecular cell, Vol. 7, Issue 3, pp. 673-82, (2001) (PubMed).
: "PUMA, a novel proapoptotic gene, is induced by p53." in: Molecular cell, Vol. 7, Issue 3, pp. 683-94, (2001) (PubMed).
: "Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11318-23, (2001) (PubMed).
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PUMA induces the rapid apoptosis of colorectal cancer cells." in: Molecular cell, Vol. 7, Issue 3, pp. 673-82, (2001) (PubMed).
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- 抗原
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- 别名
- PUMA (BBC3 产品)
- 别名
- BBC3 antibody, Puma antibody, JFY-1 antibody, JFY1 antibody, PUMA antibody, PUMA/JFY1 antibody, BCL2 binding component 3 antibody, Bcl-2 binding component 3 antibody, BBC3 antibody, Bbc3 antibody, bbc3 antibody
- 基因ID
- 27113
- 途径
- p53 Pathway, Positive Regulation of Endopeptidase Activity
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