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UNC93B1 抗体 (N-Term)

UNC93B1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN541343
发货至: 中国
  • 抗原 See all UNC93B1 抗体
    UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 17
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 16
    • 1
    克隆类型
    • 17
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNC93B1 antibody is un-conjugated
    应用范围
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic peptide of UNC93B1.
    交叉反应
    人, 小鼠, 大鼠
    免疫原
    A synthetic peptide corresponding to N-terminus 19 amino acids of human UNC93B1.
    Top Product
    Discover our top product UNC93B1 Primary Antibody
  • 应用备注
    Western Blot (0.5-1 μg/mL)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In PBS (0.02 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Panchanathan, Liu, Choubey: "Expression of murine Unc93b1 is up-regulated by interferon and estrogen signaling: implications for sex bias in the development of autoimmunity." in: International immunology, Vol. 25, Issue 9, pp. 521-9, (2013) (PubMed).

    Brinkmann, Spooner, Hoebe, Beutler, Ploegh, Kim: "The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling." in: The Journal of cell biology, Vol. 177, Issue 2, pp. 265-75, (2007) (PubMed).

    Tabeta, Hoebe, Janssen, Du, Georgel, Crozat, Mudd, Mann, Sovath, Goode, Shamel, Herskovits, Portnoy, Cooke, Tarantino, Wiltshire, Steinberg, Grinstein, Beutler: "The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9." in: Nature immunology, Vol. 7, Issue 2, pp. 156-64, (2006) (PubMed).

    Liu, Dodds, Emilion, Mungall, Dunham, Beck, Wells, Charnock, Ganesan: "The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer." in: BMC genetics, Vol. 3, pp. 20, (2002) (PubMed).

  • 抗原
    UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
    别名
    UNC93B1 (UNC93B1 产品)
    别名
    UNC93 antibody, IIAE1 antibody, UNC93B antibody, Unc-93B1 antibody, Unc93b antibody, unc-93 homolog B1, TLR signaling regulator antibody, unc-93 homolog B1 (C. elegans) antibody, UNC93B1 antibody, Unc93b1 antibody
    基因ID
    81622
    途径
    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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