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APEX1 抗体

APEX1 适用: 人 WB, IF, IHC (p), ICC, IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN540784
发货至: 中国
  • 抗原 See all APEX1 抗体
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    适用
    • 87
    • 38
    • 35
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 70
    • 18
    • 2
    克隆类型
    • 73
    • 17
    多克隆
    标记
    • 67
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APEX1 antibody is un-conjugated
    应用范围
    • 83
    • 30
    • 29
    • 27
    • 20
    • 13
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Rabbit polyclonal antibody raised against recombinant APEX1.
    特异性
    This antibody is specific to the human APE/ref-1protein.
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    Recombinant protein corresponding to human APEX1.
    Top Product
    Discover our top product APEX1 Primary Antibody
  • 应用备注
    Immunocytochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    Immunoprecipitation (7 μg/mL)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C or -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Lam, Bussom, Cheng: "Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma." in: Molecular cancer therapeutics, Vol. 8, Issue 2, pp. 415-23, (2009) (PubMed).

    Yang, Chen, Zhang, Huang, Zhang: "Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA." in: The Journal of biological chemistry, Vol. 282, Issue 16, pp. 11667-75, (2007) (PubMed).

    Raffoul, Banerjee, Singh-Gupta, Knoll, Fite, Zhang, Abrams, Sarkar, Hillman: "Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo." in: Cancer research, Vol. 67, Issue 5, pp. 2141-9, (2007) (PubMed).

    Briegert, Kaina: "Human monocytes, but not dendritic cells derived from them, are defective in base excision repair and hypersensitive to methylating agents." in: Cancer research, Vol. 67, Issue 1, pp. 26-31, (2007) (PubMed).

    Yang, DeBusk, Fukuda, Fingleton, Green-Jarvis, Shyr, Matrisian, Carbone, Lin: "Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis." in: Cancer cell, Vol. 6, Issue 4, pp. 409-21, (2004) (PubMed).

  • 抗原
    APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
    别名
    APEX1 / REF-1 (APEX1 产品)
    基因ID
    328
    途径
    DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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