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FOXO1 抗体 (pSer256)

FOXO1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN539166
发货至: 中国
  • 抗原 See all FOXO1 抗体
    FOXO1 (Forkhead Box O1 (FOXO1))
    抗原表位
    • 25
    • 21
    • 18
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    • 11
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    • 1
    • 1
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    • 1
    • 1
    • 1
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    • 1
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    pSer256
    适用
    • 231
    • 162
    • 151
    • 48
    • 30
    • 25
    • 18
    • 11
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 212
    • 21
    • 1
    • 1
    克隆类型
    • 205
    • 30
    多克隆
    标记
    • 105
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
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    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 1
    • 1
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    This FOXO1 antibody is un-conjugated
    应用范围
    • 198
    • 91
    • 78
    • 66
    • 57
    • 57
    • 44
    • 33
    • 20
    • 20
    • 8
    • 6
    • 5
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    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of FOXO1.
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide corresponding to residues surrounding S256 of human FOXO1.
    Top Product
    Discover our top product FOXO1 Primary Antibody
  • 应用备注
    Immunohistochemistry (1:50-1:100)
    Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Sajan, Ivey, Farese: "BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans." in: Metabolism: clinical and experimental, Vol. 64, Issue 11, pp. 1454-65, (2015) (PubMed).

    Sajan, Ivey, Lee, Mastorides, Jurczak, Samuels, Shulman, Braun, Leitges, Farese: "PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes." in: Molecular endocrinology (Baltimore, Md.), Vol. 28, Issue 7, pp. 1097-107, (2014) (PubMed).

    Sajan, Ivey, Lee, Farese: "Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation." in: Journal of lipid research, Vol. 56, Issue 1, pp. 70-80, (2014) (PubMed).

  • 抗原
    FOXO1 (Forkhead Box O1 (FOXO1))
    别名
    FOXO1A (FOXO1 产品)
    别名
    FKH1 antibody, FKHR antibody, FOXO1A antibody, FoxO1a.1 antibody, foxo1 antibody, zgc:153388 antibody, Fkhr antibody, Foxo1a antibody, AI876417 antibody, Afxh antibody, Fkhr1 antibody, fkh1 antibody, fkhr antibody, foxo1a antibody, xFoxO1 antibody, FoxO1A antibody, foxo1a.2 antibody, forkhead box O1 antibody, forkhead box O1 a antibody, forkhead box O1 L homeolog antibody, forkhead box O1 b antibody, FOXO1 antibody, foxo1a antibody, Foxo1 antibody, foxo1 antibody, foxo1.L antibody, foxo1b antibody
    基因ID
    2308
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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