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MTOR 抗体 (pSer2448)

mTOR 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN538478
发货至: 中国
  • 抗原 See all MTOR (mTOR) 抗体
    MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
    抗原表位
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    pSer2448
    适用
    • 210
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    宿主
    • 191
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    克隆类型
    • 172
    • 37
    多克隆
    标记
    • 107
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    This MTOR antibody is un-conjugated
    应用范围
    • 145
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of MTOR.
    特异性
    Reactivity occurs with phosphorylated mTOR from human derived tissues and cells. Reactivity with mouse and rat is suggested based on protein sequence homologies.
    交叉反应
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide corresponding to residues surrounding S2448 of human MTOR.
    Top Product
    Discover our top product mTOR Primary Antibody
  • 应用备注
    ELISA (1:15000-1:65000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (5.0 μg/mL)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Nojima, Tokunaga, Eguchi, Oshiro, Hidayat, Yoshino, Hara, Tanaka, Avruch, Yonezawa: "The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 15461-4, (2003) (PubMed).

    Kristof, Marks-Konczalik, Billings, Moss: "Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 33637-44, (2003) (PubMed).

    Chen, Zheng, Foster: "Phospholipase D confers rapamycin resistance in human breast cancer cells." in: Oncogene, Vol. 22, Issue 25, pp. 3937-42, (2003) (PubMed).

  • 抗原
    MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
    别名
    MTOR / FRAP1 (mTOR 产品)
    别名
    FRAP1 antibody, FRAP antibody, FRAP2 antibody, RAFT1 antibody, RAPT1 antibody, 2610315D21Rik antibody, AI327068 antibody, Frap1 antibody, flat antibody, frap1 antibody, tor antibody, wu:fc22h08 antibody, mechanistic target of rapamycin kinase antibody, mechanistic target of rapamycin antibody, mechanistic target of rapamycin (serine/threonine kinase) antibody, MTOR antibody, Mtor antibody, mtor antibody
    基因ID
    2475
    途径
    PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
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