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MDM2 抗体 (pSer185)

MDM2 适用: 小鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN538477
发货至: 中国
  • 抗原 See all MDM2 抗体
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    抗原表位
    • 26
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    pSer185
    适用
    • 195
    • 80
    • 55
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 170
    • 28
    • 1
    克隆类型
    • 170
    • 29
    多克隆
    标记
    • 100
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    • 2
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    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    This MDM2 antibody is un-conjugated
    应用范围
    • 126
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    原理
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of Mdm2.
    特异性
    Reactivity occurs against Mouse MDM2 pS185 protein and This antibody is specific to the phosphorylated form of the protein. Reactivity with non-phosphorylated mouse MDM2 is minimal by ELISA and western blot.
    交叉反应
    小鼠
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide corresponding to residues surrounding S185 of mouse Mdm2.
    Top Product
    Discover our top product MDM2 Primary Antibody
  • 应用备注
    ELISA (1:3000-1:12000)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Stros, Muselíková-Polanská, Pospísilová, Strauss: "High-affinity binding of tumor-suppressor protein p53 and HMGB1 to hemicatenated DNA loops." in: Biochemistry, Vol. 43, Issue 22, pp. 7215-25, (2004) (PubMed).

    Aslanian, Iaquinta, Verona, Lees: "Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics." in: Genes & development, Vol. 18, Issue 12, pp. 1413-22, (2004) (PubMed).

    Pospísilová, Siligan, Ban, Jug, Kovar: "Constitutive and DNA damage inducible activation of pig3 and MDM2 genes by tumor-derived p53 mutant C277Y." in: Molecular cancer research : MCR, Vol. 2, Issue 5, pp. 296-304, (2004) (PubMed).

  • 抗原
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    别名
    MDM2 (MDM2 产品)
    别名
    ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody
    基因ID
    17246
    途径
    p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway
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