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Huntingtin 抗体 (pSer421)

HTT 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN538469
发货至: 中国
  • 抗原 See all Huntingtin (HTT) 抗体
    Huntingtin (HTT)
    抗原表位
    • 15
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer421
    适用
    • 66
    • 46
    • 38
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 62
    • 22
    • 2
    克隆类型
    • 54
    • 31
    多克隆
    标记
    • 58
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Huntingtin antibody is un-conjugated
    应用范围
    • 43
    • 33
    • 27
    • 14
    • 14
    • 13
    • 13
    • 9
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    原理
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of HTT.
    特异性
    This antibody is specific to phosphorylated human Huntingtin protein at the pS421 residue. Minimal reactivity isexpected with the non-phosphorylated form of the protein.
    交叉反应
    小鸡, Chimpanzee, 人, Pig
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide corresponding to residues surrounding S421 of human HTT.
    Top Product
    Discover our top product HTT Primary Antibody
  • 应用备注
    ELISA (1:10000-1:40000)
    Western Blot (1:500-1:3000)
    Immunohistochemistry (1:50-1:100)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Lee, Yoshihara, Littleton: "Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 9, pp. 3224-9, (2004) (PubMed).

    Zainelli, Ross, Troncoso, Fitzgerald, Muma: "Calmodulin regulates transglutaminase 2 cross-linking of huntingtin." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 8, pp. 1954-61, (2004) (PubMed).

    Trushina, Dyer, Badger, Ure, Eide, Tran, Vrieze, Legendre-Guillemin, McPherson, Mandavilli, Van Houten, Zeitlin, McNiven, Aebersold, Hayden, Parisi, Seeberg, Dragatsis, Doyle, Bender, Chacko, McMurray: "Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro." in: Molecular and cellular biology, Vol. 24, Issue 18, pp. 8195-209, (2004) (PubMed).

  • 抗原
    Huntingtin (HTT)
    别名
    Huntingtin (HTT 产品)
    别名
    HTT antibody, hd antibody, ZHD antibody, CG9995 antibody, Dmel\\CG9995 antibody, HD antibody, Hsap\\HD antibody, Htt antibody, dHtt antibody, dhtt antibody, SLC6A4 antibody, huntington antibody, it15 antibody, htt antibody, IT15 antibody, AI256365 antibody, C430023I11Rik antibody, Hd antibody, Hdh antibody, huntingtin antibody, HTT antibody, htt antibody, LOC373520 antibody, Htt antibody
    基因ID
    3064
    途径
    PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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