BAD 抗体 (BCL2-Associated Agonist of Cell Death) (pSer112)

Details for Product anti-BAD Antibody No. ABIN537567
抗原
抗原表位
pSer112, pSer75
62
58
53
52
46
46
45
38
28
24
24
18
18
18
18
18
18
18
17
17
17
17
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17
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17
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8
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3
3
3
3
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2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
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1
1
适用

790
470
321
19
19
8
5
4
3
2
2
1
1
1
1
1
宿主

983
40
2
1
克隆类型
多克隆
标记
This BAD antibody is un-conjugated
74
67
67
63
62
61
12
12
12
12
12
12
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
548
517
383
329
109
79
35
35
19
19
7
7
5
3
2
1
1
1
1
选项
原理 Rabbit polyclonal antibody raised against synthetic phosphopeptide of BAD.
免疫原 Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S75 of human BAD.
抗原
别名 Bcl-2-like 8 (BAD Antibody 摘要)
途径 MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
应用备注 Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
限制 仅限研究用
缓冲液 In PBS (0.09 % sodium azide)
储存条件 4 °C,-20 °C
储存方法 Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
厂商提供的图像
Image no. 1 for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer112), (pSer75) antibody (ABIN537567) Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted wi...
Image no. 2 for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer112), (pSer75) antibody (ABIN537567) The BAD (phospho S75) polyclonal antibody is used in Western blot to detect Phospho-...
有引用在: Ying, Seiffert, Häcker, Fischer: "Broad degradation of proapoptotic proteins with the conserved Bcl-2 homology domain 3 during infection with Chlamydia trachomatis." in: Infection and immunity, Vol. 73, Issue 3, pp. 1399-403, 2005 (PubMed).

Antignani, Youle: "A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad." in: Biochemistry, Vol. 44, Issue 10, pp. 4074-82, 2005 (PubMed).

Hurbin, Coll, Dubrez-Daloz, Mari, Auberger, Brambilla, Favrot: "Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells." in: The Journal of biological chemistry, Vol. 280, Issue 20, pp. 19757-67, 2005 (PubMed).